Sinus surgery for patients with allergy
Postoperative care for Samter’s triad patients undergoing endoscopic sinus surgery: A double-blinded, randomized controlled trial
Brian W. Rotenberg MD, MPH, et al.
The Laryngoscope. Volume 121, Issue 12, pages 2702–2705, December 2011
The purpose of this study was to compare three different standardized medication regimens prescribed to patients after endoscopic sinus surgery (ESS)
Patients with Samter’s triad undergoing ESS were postoperatively randomized into three medication regimens:
- Control group A – those using saline irrigation alone
- Group B – saline irrigation plus separate budesonide nasal spray
- Group C – saline irrigation mixed with budesonide nasal spray
Outcome measures were Sino-Nasal Outcome Test scores, Lund-Mackay computed tomography scores, and Lund-Kennedy endoscopic scores taken at preoperative baseline, and then at 6 months and 1 year postoperatively
Side effect profiles were also measured
Results:
Sixty subjects were recruited
All groups were equivalent at baseline in all outcomes
All intragroup analyses showed statistically and clinically significant improvement in disease status as compared to baseline (P< .0167), with a sustained but lessened improvement at 1 year
However, no statistically or clinically significant differences were observed between groups at any time point
Conclusions:
In this study, nasal steroids did not confer any additional benefit over saline alone as post-ESS care
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